The Visual Expectation Paradigm (M. M. Haith et al, 1988) was modified to assess the role that picture content plays in the spatiotemporal expectations of 2- and 3-mo-old infants. Infants watched pictures of 700-msec duration that appeared in left–right alternation with a 1,000-msec interstimulus interval. The same picture occurred repeatedly on one side, in alternation with an unpredictable picture on the other side. Across 3 studies, the unchanging picture, rather than engendering habituation, produced higher levels of anticipation and speeded reactions. Thus, infants used the stable picture-content information to facilitate formation of expectations about when and where pictures would appear. Although 2-mo-olds were consistently slower than 3-mo-olds, their reaction times (RTs) benefited more from predictability than did the RTs of older infants. The percentage of anticipatory fixations did not differ between the 2 age groups.